INT239270

Context Info Confidence 0.27 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 1 Disease Relevance 1.21 Pain Relevance 0.03

endosome (Abcg1) transport (Abcg1) Golgi apparatus (Abcg1) ATPase activity (Abcg1) plasma membrane (Abcg1) intracellular (Abcg1)

Anatomy Link Frequency Liver 1 Abcg1 (Mus musculus)

Pain Link Frequency Relevance Heat agonist 15 55.36 alcohol 11 5.00 Inflammation 9 5.00 Bile 4 5.00 Angina 3 5.00 ischemia 2 5.00 cytokine 1 5.00 Nicotine 1 5.00 imagery 1 5.00 Potency 1 5.00

Disease Link Frequency Relevance Heat Disorder Of Lipid Metabolism 288 99.20 Targeted Disruption 10 81.32 Atherosclerosis 49 74.20 Atherosclerotic Plaque 3 66.04 Insulin Resistance 2 62.32 Metabolic Syndrome 1 60.16 Hypolipidemia 2 36.84 Coronary Heart Disease 33 5.00 Myocardial Infarction 19 5.00 Cardiovascular Disease 11 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

Transcription of both ABCA1 and ABCG1 is regulated by members of a steroid superfamily of nuclear receptors known as the Liver X receptor/Retinoid X receptor (LXR/RXR) heterodimer.

Transcription (Transcription) of ABCG1 in Liver

1) Confidence 0.27 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.21 Pain Relevance 0.03

General Comments

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