INT239287

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Context Info
Confidence 0.32
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.87
Pain Relevance 0.21

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Abca1) Golgi apparatus (Abca1) ATPase activity (Abca1)
plasma membrane (Abca1) intracellular (Abca1)
Anatomy Link Frequency
Liver 1
Abca1 (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 30 93.44 High High
Inflammation 18 71.36 Quite High
ischemia 4 34.48 Quite Low
alcohol 22 5.00 Very Low Very Low Very Low
Bile 8 5.00 Very Low Very Low Very Low
Angina 6 5.00 Very Low Very Low Very Low
cytokine 2 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 576 99.20 Very High Very High Very High
Targeted Disruption 20 81.32 Quite High
Atherosclerosis 98 74.88 Quite High
INFLAMMATION 16 71.36 Quite High
Atherosclerotic Plaque 6 66.04 Quite High
Insulin Resistance 4 61.52 Quite High
Metabolic Syndrome 2 59.36 Quite High
Hypolipidemia 4 36.84 Quite Low
Reperfusion Injury 4 35.24 Quite Low
Cv Unclassified Under Development 2 34.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Hydroxylated cholesterol stimulates LXR-mediated transcription of ABCA1, which subsequently enhances RCT from peripheral tissues (Lund et al 2006).
Transcription (transcription) of ABCA1
1) Confidence 0.32 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 0.66 Pain Relevance 0.18
Transcription of both ABCA1 and ABCG1 is regulated by members of a steroid superfamily of nuclear receptors known as the Liver X receptor/Retinoid X receptor (LXR/RXR) heterodimer.
Transcription (Transcription) of ABCA1 in Liver
2) Confidence 0.32 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.21 Pain Relevance 0.03

General Comments

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