INT239289
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
When activated by oxysterols from FC this heterodimer stimulates ABCA1 and ABCG1 gene expression, thereby enhancing cholesterol efflux (Vaughan and Oram 2005; Venkateswaran et al 2000). | |||||||||||||||
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Moreover, the authors showed that SXR can also induce ABCA1 and ABCG1 expression and promote cholesterol efflux in the same cells. | |||||||||||||||
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and increase expression of ABCA-1 and ABCG-1 but they are not therapeutically usable as such. | |||||||||||||||
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General Comments
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