INT2393

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Context Info
Confidence 0.69
First Reported 1979
Last Reported 2010
Negated 4
Speculated 8
Reported most in Abstract
Documents 174
Total Number 182
Disease Relevance 93.59
Pain Relevance 26.79

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (Mb)
Anatomy Link Frequency
blood 15
chest 14
muscle 14
plasma 11
smooth muscle 3
Mb (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Pain 111 99.92 Very High Very High Very High
ketamine 18 99.84 Very High Very High Very High
halothane 34 99.74 Very High Very High Very High
Angina 167 99.62 Very High Very High Very High
cva 20 99.50 Very High Very High Very High
visual analogue scale 1 98.84 Very High Very High Very High
imagery 13 97.88 Very High Very High Very High
anesthesia 61 97.64 Very High Very High Very High
opiate 2 97.50 Very High Very High Very High
cocaine 9 97.32 Very High Very High Very High
Disease Link Frequency Relevance Heat
Myocardial Infarction 359 100.00 Very High Very High Very High
Necrosis 46 100.00 Very High Very High Very High
Disorders Of Creatine Metabolism 40 100.00 Very High Very High Very High
Pain 71 99.92 Very High Very High Very High
Fever 53 99.90 Very High Very High Very High
Rhabdomyolysis 82 99.88 Very High Very High Very High
Myalgia 43 99.88 Very High Very High Very High
Injury 57 99.70 Very High Very High Very High
Emergencies 52 99.68 Very High Very High Very High
Angina 118 99.62 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Increased serum myoglobin levels were detected by radioimmunoassay in 57 (71.8%) of 80 patients with unstable angina.
Positive_regulation (Increased) of myoglobin associated with angina
1) Confidence 0.69 Published 1986 Journal Kardiologiia Section Abstract Doc Link 3784264 Disease Relevance 0.17 Pain Relevance 0.25
Sensitivity and specificity for detecting acute myocardial infarction for a twofold increase in myoglobin level from baseline were 39% and 98%, respectively.
Positive_regulation (increase) of myoglobin associated with myocardial infarction
2) Confidence 0.69 Published 1999 Journal Am. J. Cardiol. Section Abstract Doc Link 10073855 Disease Relevance 0.81 Pain Relevance 0.18
The Myolex (Orion) and the RapiTex (Behringwerke) latex agglutination tests for the rapid detection of elevated levels of serum myoglobin were studied prospectively in patients suspected of acute myocardial infarction, who were admitted to hospital within 8 h of pain onset.
Positive_regulation (elevated) of myoglobin associated with pain and myocardial infarction
3) Confidence 0.68 Published 1989 Journal Ann. Clin. Biochem. Section Abstract Doc Link 2764470 Disease Relevance 0.41 Pain Relevance 0.09
After repeated massage treatment a gradual decline in the increase in plasma myoglobin concentration could be demonstrated parallel to a reduction in the muscle tension and pain.
Positive_regulation (increase) of myoglobin in muscle associated with pain
4) Confidence 0.68 Published 1986 Journal Scand. J. Rheumatol. Section Abstract Doc Link 3462906 Disease Relevance 0.56 Pain Relevance 0.50
The observed increase in myoglobin in plasma after massage indicates a leak of myoglobin from the muscle fibres in 21 patients, whose myofascial pain seem to be linked with a muscle fibre disease.
Positive_regulation (increase) of myoglobin in muscle associated with snapping jaw and disease
5) Confidence 0.68 Published 1986 Journal Scand. J. Rheumatol. Section Abstract Doc Link 3462906 Disease Relevance 0.61 Pain Relevance 0.51
The observed increase of myoglobin in plasma after massage indicates a leak of myoglobin from the muscle fibres, which suggests that regional muscle tension and pain is associated with disorders in the muscle fibres.
Positive_regulation (increase) of myoglobin in plasma associated with pain
6) Confidence 0.68 Published 1983 Journal Scand J Rehabil Med Section Abstract Doc Link 6572411 Disease Relevance 0.49 Pain Relevance 0.41
An increase in the activities of enzymes of muscular origin and of myoglobin in serum was found and myoglobinuria was detected.
Positive_regulation (increase) of myoglobin associated with myoglobinuria
7) Confidence 0.68 Published 1981 Journal Med Klin Section Abstract Doc Link 7345362 Disease Relevance 0.47 Pain Relevance 0.10
The level of myoglobin in the blood of patients with primary transmural myocardial infarction was rapidly increased, reaching its maximum in 9-12 h and returning to normal in 9 days.
Positive_regulation (increased) of myoglobin in blood associated with myocardial infarction
8) Confidence 0.68 Published 1987 Journal Ter. Arkh. Section Abstract Doc Link 3629507 Disease Relevance 0.52 Pain Relevance 0.03
From the differential diagnostic aspect it is particularly valuable that myoglobin was not elevated in any patient with embolism of the pulmonary artery and only very rarely in angina pectoris.
Neg (not) Positive_regulation (elevated) of myoglobin in pulmonary artery associated with cva
9) Confidence 0.68 Published 1991 Journal Vnitr Lek Section Abstract Doc Link 2053302 Disease Relevance 1.58 Pain Relevance 0.59
Where in exceptional instances the myoglobin levels were elevated in patients with other investigated causes of chest pain, this increase was always due to another basic disease (right-sided cardiac failure, renal insufficiency, neuromuscular disease), whereby for these conditions prolonged persistence of the elevated serum myoglobin values was typical and the levels were never above 8 nmol/l.
Spec (investigated) Positive_regulation (elevated) of myoglobin in chest associated with angina, neuromuscular disease, renal insufficiency, disease and myocardial infarction
10) Confidence 0.68 Published 1991 Journal Vnitr Lek Section Abstract Doc Link 2053302 Disease Relevance 1.60 Pain Relevance 0.58
Five patients did not benefit from massage treatment and no significant increase in the myoglobin in plasma was measured.
Neg (no) Positive_regulation (increase) of myoglobin in plasma
11) Confidence 0.68 Published 1986 Journal Scand. J. Rheumatol. Section Abstract Doc Link 3462906 Disease Relevance 0.59 Pain Relevance 0.51
The type of anesthetic agent used influences the extent of the increase in serum myoglobin concentrations brought about by succinylcholine (sch).
Positive_regulation (increase) of myoglobin
12) Confidence 0.68 Published 1987 Journal Anaesthesist Section Abstract Doc Link 3661948 Disease Relevance 0.07 Pain Relevance 0.23
In 77 patients with acute myocardial infarction (M.I.) (64 patients with acute transmural and 13 with acute subendocardial M.I.), the myoglobin values were significantly increased.
Positive_regulation (increased) of myoglobin associated with myocardial infarction
13) Confidence 0.67 Published 1982 Journal Acta Cardiol Section Abstract Doc Link 6981904 Disease Relevance 0.35 Pain Relevance 0.10
The ANN was compared with serum myoglobin measurements--cardiac damage is associated with increased circulating myoglobin levels, and this is widely used as an early marker for evolving AMI.
Positive_regulation (increased) of myoglobin associated with myocardial infarction
14) Confidence 0.66 Published 1997 Journal Comput Methods Programs Biomed Section Abstract Doc Link 9034674 Disease Relevance 0.77 Pain Relevance 0.18
Admission myoglobin was elevated in 47 of 52 patients with acute infarction.
Positive_regulation (elevated) of myoglobin associated with infarction
15) Confidence 0.63 Published 1979 Journal J. Nucl. Med. Section Abstract Doc Link 430183 Disease Relevance 0.64 Pain Relevance 0.08
In 22 of 105 patients with no infarct, myoglobin was elevated in association with angina, congestive heart failure, arrhythmias, and renal insufficiency.
Positive_regulation (elevated) of myoglobin in heart associated with heart rate under development, angina and renal insufficiency
16) Confidence 0.63 Published 1979 Journal J. Nucl. Med. Section Abstract Doc Link 430183 Disease Relevance 0.73 Pain Relevance 0.10
The detection of acute infarction by serum myoglobin measurement equals that of serial serum creatine phosphokinase isoenzymes (CPK-MB) by electrophoresis, but an elevated myoglobin is not specific for what is now considered clinically significant myocardial infarction.
Positive_regulation (elevated) of myoglobin associated with disorders of creatine metabolism, infarction and myocardial infarction
17) Confidence 0.63 Published 1979 Journal J. Nucl. Med. Section Abstract Doc Link 430183 Disease Relevance 0.80 Pain Relevance 0.09
When the upper extremity was cooled with ice water before application of the tourniquet, however, the increase of serum myoglobin was statistically significantly inhibited when compared with the normothermic condition.
Positive_regulation (increase) of serum myoglobin in upper
18) Confidence 0.60 Published 1988 Journal Clin. Orthop. Relat. Res. Section Abstract Doc Link 3409588 Disease Relevance 0.07 Pain Relevance 0.18
Serum myoglobin levels have been found to be elevated for a few hours after removal of a tourniquet.
Positive_regulation (elevated) of Serum myoglobin
19) Confidence 0.60 Published 1988 Journal Clin. Orthop. Relat. Res. Section Abstract Doc Link 3409588 Disease Relevance 0.07 Pain Relevance 0.10
Serum myoglobin was increased after exposure and remained elevated for the 3-h follow-up period.
Positive_regulation (increased) of myoglobin
20) Confidence 0.60 Published 2009 Journal Forensic science, medicine, and pathology Section Abstract Doc Link 19330471 Disease Relevance 0.16 Pain Relevance 0.08

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