INT23930

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Context Info
Confidence 0.44
First Reported 1987
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.05
Pain Relevance 0.18

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

protein modification process (ST8SIA2) Golgi apparatus (ST8SIA2) carbohydrate metabolic process (ST8SIA2)
ST8SIA2 (Homo sapiens)
Pain Link Frequency Relevance Heat
addiction 1 100.00 Very High Very High Very High
tetrodotoxin 1 93.52 High High
sodium channel 2 75.00 Quite High
Piles 4 5.00 Very Low Very Low Very Low
headache 3 5.00 Very Low Very Low Very Low
conotoxin 2 5.00 Very Low Very Low Very Low
Ziconotide 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
Lasting pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Shellfish Poisoning 11 54.48 Quite High
Toxicity 12 5.00 Very Low Very Low Very Low
Anorectal Disorders 4 5.00 Very Low Very Low Very Low
Sprains And Strains 3 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Poisoning 2 5.00 Very Low Very Low Very Low
Death 2 5.00 Very Low Very Low Very Low
Tension-type Headache 2 5.00 Very Low Very Low Very Low
Frailty 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Modifications of gating by lipophilic toxins confer a selective voltage-dependence on STX and TTX inhibition of open channels that is not observed in drug-free channels.
Regulation (voltage-dependence) of STX associated with addiction
1) Confidence 0.44 Published 1987 Journal Annu. Rev. Neurosci. Section Abstract Doc Link 2436544 Disease Relevance 0 Pain Relevance 0.18
Proteomic and transcriptomic studies are likely to provide a link between STX biosynthesis, regulation and cellular metabolism.
Regulation (regulation) of STX
2) Confidence 0.06 Published 2010 Journal Marine Drugs Section Body Doc Link PMC2920551 Disease Relevance 0.05 Pain Relevance 0

General Comments

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