INT239315

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Context Info
Confidence 0.30
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

lipid binding (CETP) transport (CETP) extracellular space (CETP)
small molecule metabolic process (CETP) extracellular region (CETP) lipid metabolic process (CETP)
CETP (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 4 74.00 Quite High
agonist 15 5.00 Very Low Very Low Very Low
alcohol 11 5.00 Very Low Very Low Very Low
Inflammation 9 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 288 98.52 Very High Very High Very High
Coronary Heart Disease 33 83.92 Quite High
Obesity 1 77.48 Quite High
Atherosclerosis 49 77.36 Quite High
Cancer 2 59.60 Quite High
Targeted Disruption 10 48.88 Quite Low
Renal Failure 1 42.36 Quite Low
Anaemia 1 41.64 Quite Low
Disease 5 39.56 Quite Low
Syndrome 1 34.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Heterozygotes with a 40% decrease in CETP levels had a mean increase in HDL-C of 30% and no significant change in LDL-C levels, while homozygotes with complete loss of CETP levels had a greater than 100% increase in HDL-C and 40% decrease in LDL-C and Apo B levels (Inazu et al 1990; Koizumi et al 1991).
Negative_regulation (loss) of Gene_expression (levels) of CETP associated with disorder of lipid metabolism
1) Confidence 0.30 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.09 Pain Relevance 0.04

General Comments

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