INT239336

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Context Info
Confidence 0.07
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.84
Pain Relevance 0.29

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Nr1h2, Fas) cytoplasm (Nr1h2, Fas) signal transduction (Fas)
extracellular region (Fas) plasma membrane (Fas) DNA binding (Nr1h2)
Nr1h2 (Mus musculus)
Fas (Mus musculus)
Pain Link Frequency Relevance Heat
agonist 15 100.00 Very High Very High Very High
Inflammation 9 70.48 Quite High
alcohol 11 5.00 Very Low Very Low Very Low
Bile 4 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyperlipidemia 2 92.56 High High
Disorder Of Lipid Metabolism 288 89.60 High High
Atherosclerosis 49 87.12 High High
Targeted Disruption 10 84.68 Quite High
INFLAMMATION 8 70.48 Quite High
Vasculitis 1 49.52 Quite Low
Diabetes Mellitus 3 24.16 Low Low
Atherosclerotic Plaque 3 7.16 Low Low
Coronary Heart Disease 33 5.00 Very Low Very Low Very Low
Myocardial Infarction 19 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Since LXR agonists induce genes that stimulate lipogenesis, including the sterol response element binding protein (SREBP1-c) and fatty acid synthetase (FAS).
LXR Positive_regulation (induce) of Gene_expression (acid synthetase) of FAS associated with agonist
1) Confidence 0.07 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 0.84 Pain Relevance 0.29

General Comments

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