INT239339

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.43
Pain Relevance 0.13

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
endothelial cells 2
Hdl1 (Mus musculus)
Paf (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 9 71.76 Quite High
Bile 4 40.48 Quite Low
cytokine 1 22.48 Low Low
agonist 15 5.00 Very Low Very Low Very Low
alcohol 11 5.00 Very Low Very Low Very Low
Angina 3 5.00 Very Low Very Low Very Low
ischemia 2 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Potency 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 288 100.00 Very High Very High Very High
Adhesions 2 97.96 Very High Very High Very High
Coronary Heart Disease 33 92.32 High High
Atherosclerosis 49 87.08 High High
Toxicity 1 85.44 High High
Myocardial Infarction 19 82.64 Quite High
INFLAMMATION 8 71.76 Quite High
Thrombosis 2 66.60 Quite High
Atherosclerotic Plaque 3 55.68 Quite High
Cancer 2 46.56 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HDL-C inhibits PAF production by endothelial cells in dose-dependent manner (Sugatani et al 1996) via hydrolysis of acetyl residues mediated by PAFAH.
HDL Negative_regulation (inhibits) of Gene_expression (production) of PAF in endothelial cells associated with disorder of lipid metabolism
1) Confidence 0.02 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.43 Pain Relevance 0.13

General Comments

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