INT239349

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 3.37
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Tbxa2r) plasma membrane (Tbxa2r) signal transducer activity (Tbxa2r)
Anatomy Link Frequency
platelet 2
Hdl1 (Mus musculus)
Tbxa2r (Mus musculus)
Pain Link Frequency Relevance Heat
cytokine 2 39.92 Quite Low
Inflammation 18 39.56 Quite Low
ischemia 4 20.00 Low Low
agonist 30 5.00 Very Low Very Low Very Low
alcohol 22 5.00 Very Low Very Low Very Low
Bile 8 5.00 Very Low Very Low Very Low
Angina 6 5.00 Very Low Very Low Very Low
Nicotine 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Potency 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 576 100.00 Very High Very High Very High
Atherosclerosis 98 90.48 High High
Apoptosis 6 87.32 High High
Myocardial Infarction 38 69.36 Quite High
Coronary Heart Disease 66 54.08 Quite High
Coronary Artery Disease 12 48.96 Quite Low
INFLAMMATION 16 39.56 Quite Low
Increased Venous Pressure Under Development 2 39.20 Quite Low
Adhesions 4 32.52 Quite Low
Necrosis 2 28.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
HDL-C inhibits platelet aggregation by blocking thromboxane-A2 (TXA2) and PAF activity, while stimulating nitric oxide (NO) and PGI2 synthesis (Saku et al 1985; Naqvi et al 1999).
HDL Negative_regulation (blocking) of thromboxane-A2 in platelet associated with disorder of lipid metabolism
1) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.68 Pain Relevance 0
HDL-C inhibits platelet aggregation by blocking thromboxane-A2 (TXA2) and PAF activity, while stimulating nitric oxide (NO) and PGI2 synthesis (Saku et al 1985; Naqvi et al 1999).
HDL Negative_regulation (blocking) of TXA2 in platelet associated with disorder of lipid metabolism
2) Confidence 0.03 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.69 Pain Relevance 0

General Comments

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