INT239355

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Context Info
Confidence 0.17
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.75
Pain Relevance 0.14

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transport (CETP) small molecule metabolic process (CETP) DNA binding (Nr1h2)
lipid metabolic process (CETP) cytoplasm (Nr1h2) lipid binding (CETP)
Anatomy Link Frequency
adipose tissue 7
liver 1
spleen 1
Nr1h2 (Mus musculus)
CETP (Homo sapiens)
Pain Link Frequency Relevance Heat
Bile 12 96.44 Very High Very High Very High
agonist 45 5.00 Very Low Very Low Very Low
alcohol 33 5.00 Very Low Very Low Very Low
Inflammation 27 5.00 Very Low Very Low Very Low
Angina 9 5.00 Very Low Very Low Very Low
ischemia 6 5.00 Very Low Very Low Very Low
cytokine 3 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
imagery 3 5.00 Very Low Very Low Very Low
Potency 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Obesity 3 99.96 Very High Very High Very High
Disorder Of Lipid Metabolism 864 91.52 High High
Coronary Heart Disease 99 83.16 Quite High
Targeted Disruption 30 71.32 Quite High
Atherosclerosis 147 66.68 Quite High
Renal Failure 3 64.80 Quite High
Anaemia 3 64.08 Quite High
Disease 15 62.00 Quite High
Syndrome 3 56.56 Quite High
Eye Disease 3 55.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Found predominantly in the liver, spleen, and adipose tissue, expression of CETP is enhanced by hypercholesterolemic diets via activation of a sterol regulatory protein and through binding of oxysterols to the LXR/RXR receptor (De Grooth et al 2004).
LXR Binding (binding) of in adipose tissue Positive_regulation (enhanced) of Gene_expression (expression) of CETP in adipose tissue associated with obesity
1) Confidence 0.17 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.25 Pain Relevance 0.05
Found predominantly in the liver, spleen, and adipose tissue, expression of CETP is enhanced by hypercholesterolemic diets via activation of a sterol regulatory protein and through binding of oxysterols to the LXR/RXR receptor (De Grooth et al 2004).
LXR Binding (binding) of in adipose tissue Positive_regulation (enhanced) of in liver Gene_expression (expression) of CETP in adipose tissue associated with obesity
2) Confidence 0.06 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.25 Pain Relevance 0.05
Found predominantly in the liver, spleen, and adipose tissue, expression of CETP is enhanced by hypercholesterolemic diets via activation of a sterol regulatory protein and through binding of oxysterols to the LXR/RXR receptor (De Grooth et al 2004).
LXR Binding (binding) of in adipose tissue Positive_regulation (enhanced) of in spleen Gene_expression (expression) of CETP in adipose tissue associated with obesity
3) Confidence 0.06 Published 2008 Journal Vascular Health and Risk Management Section Body Doc Link PMC2464766 Disease Relevance 1.25 Pain Relevance 0.05

General Comments

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