INT239436

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Context Info
Confidence 0.54
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 3
Total Number 3
Disease Relevance 0.67
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (PPOX) small molecule metabolic process (PPOX) oxidoreductase activity (PPOX)
PPOX (Homo sapiens)
Pain Link Frequency Relevance Heat
alcohol 2 18.40 Low Low
Central nervous system 2 14.08 Low Low
abdominal pain 2 9.76 Low Low
addiction 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Variegate Porphyria 84 95.20 Very High Very High Very High
Death 4 79.88 Quite High
Porphyria 20 49.44 Quite Low
Infection 2 21.32 Low Low
Overnutrition 2 20.84 Low Low
Fever 2 12.08 Low Low
Heart Rate Under Development 2 11.80 Low Low
Hypertension 2 11.28 Low Low
Vomiting 2 10.72 Low Low
Constipation 2 10.32 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The 5 kb PPOX gene is localized on chromosome 1q2.2-2.3 and contains one non-coding and 12 coding exons [18-20].
Localization (localized) of PPOX gene
1) Confidence 0.54 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2467414 Disease Relevance 0.51 Pain Relevance 0
DNA isolation and PPOX gene amplification
Localization (amplification) of PPOX gene
2) Confidence 0.50 Published 2008 Journal BMC Med Genet Section Body Doc Link PMC2467414 Disease Relevance 0.15 Pain Relevance 0
In contrast to laccase and bilirubin oxidase, PPO could efficiently operate at pH 7 and was not inhibited by products present in physiological fluids.
Localization (bilirubin oxidase) of PPO
3) Confidence 0.08 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2864295 Disease Relevance 0 Pain Relevance 0

General Comments

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