INT239500

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Context Info
Confidence 0.20
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.40
Pain Relevance 0.56

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

mitochondrion (Atic) nucleus (Aes)
Aes (Mus musculus)
Atic (Mus musculus)
Pain Link Frequency Relevance Heat
methotrexate 35 99.84 Very High Very High Very High
adenocard 14 97.16 Very High Very High Very High
Inflammation 4 85.64 High High
antagonist 2 58.24 Quite High
Central nervous system 3 53.12 Quite High
central sensitization 1 34.24 Quite Low
agonist 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
headache 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Rheumatoid Arthritis 15 99.60 Very High Very High Very High
INFLAMMATION 4 85.64 High High
Vomiting 5 84.16 Quite High
Ganglion Cysts 1 48.64 Quite Low
Panic Disorder 1 10.96 Low Low
Anxiety Disorder 1 9.04 Low Low
Toxicity 5 5.00 Very Low Very Low Very Low
Disease 2 5.00 Very Low Very Low Very Low
Arthritis 1 5.00 Very Low Very Low Very Low
Headache 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
While this is the first study of ADORA2a receptor polymorphisms in RA, others have shown associations between ATIC polymorphisms and AEs on MTX [14], specifically GI AEs [11] supporting the concept that the adenosine pathway is important in determining AEs on MTX.
AEs Binding (associations) of ATIC associated with adenocard, rheumatoid arthritis and methotrexate
1) Confidence 0.20 Published 2008 Journal Rheumatology (Oxford, England) Section Body Doc Link PMC2468887 Disease Relevance 0.40 Pain Relevance 0.56

General Comments

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