INT239540

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Context Info
Confidence 0.15
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 0.09
Pain Relevance 0.33

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleoplasm (MYC) intracellular (CXCR2) DNA binding (MYC)
protein complex (MYC) signal transducer activity (CXCR2) signal transduction (CXCR2)
CXCR2 (Homo sapiens)
MYC (Homo sapiens)
Pain Link Frequency Relevance Heat
opioid receptor 38 97.16 Very High Very High Very High
Potency 6 76.16 Quite High
MU agonist 16 74.96 Quite High
chemokine 30 72.64 Quite High
imagery 8 69.92 Quite High
agonist 38 51.80 Quite High
Enkephalin 10 42.32 Quite Low
antagonist 26 5.00 Very Low Very Low Very Low
Opioid 10 5.00 Very Low Very Low Very Low
narcan 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Bordatella Infection 16 88.20 High High
INFLAMMATION 10 5.00 Very Low Very Low Very Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 6 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Stomatitis 2 5.00 Very Low Very Low Very Low
Inflammatory Pain 2 5.00 Very Low Very Low Very Low
Infection 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
i2 linked to c-Myc–I148E CXCR2 and is entirely consistent with the other observations of hCXCR2–hDOP opioid receptor hetero-oligomerization (Figures 1 and 2).
CXCR2 Binding (linked) of c-Myc associated with opioid receptor
1) Confidence 0.15 Published 2008 Journal Biochemical Journal Section Body Doc Link PMC2474558 Disease Relevance 0.09 Pain Relevance 0.19
Only with co-expression of FLAG–hCXCR2 and c-Myc–hDOP did immunoprecipitation with an anti-FLAG antibody result in co-immunoprecipitation of c-Myc immunoreactivity (Figure 1) and, even in SDS/PAGE, such immunoreactivity migrated with sizes ranging from 60 kDa to complexes with a substantially higher apparent molecular mass.
hCXCR2 Binding (immunoprecipitation) of c-Myc
2) Confidence 0.13 Published 2008 Journal Biochemical Journal Section Body Doc Link PMC2474558 Disease Relevance 0 Pain Relevance 0.14

General Comments

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