INT239596

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Context Info
Confidence 0.40
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 29
Total Number 30
Disease Relevance 9.92
Pain Relevance 2.80

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transferase activity, transferring glycosyl groups (POMT1) endoplasmic reticulum (POMT1) extracellular matrix organization (POMT1)
carbohydrate metabolic process (POMT1)
Anatomy Link Frequency
plasma 3
lateral 2
medial 2
skeletal muscle 1
brain 1
POMT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
imagery 892 99.84 Very High Very High Very High
cytokine 157 94.32 High High
Pain 83 92.08 High High
Angina 4 89.84 High High
depression 5 88.40 High High
ischemia 4 72.64 Quite High
Inflammation 21 67.32 Quite High
tolerance 35 43.92 Quite Low
IPN 4 40.96 Quite Low
reflex sympathetic dystrophy 18 24.72 Low Low
Disease Link Frequency Relevance Heat
Radiation Pneumonitis 168 99.72 Very High Very High Very High
Acquired Immune Deficiency Syndrome Or Hiv Infection 50 99.56 Very High Very High Very High
Metastasis 24 99.56 Very High Very High Very High
Cancer 292 98.88 Very High Very High Very High
Enzootic Bovine Leukosis 2 97.32 Very High Very High Very High
Handedness 522 96.88 Very High Very High Very High
Cognitive Disorder 142 96.20 Very High Very High Very High
Stress 39 94.28 High High
Hypesthesia 12 94.12 High High
Pain 83 92.08 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The stability of these three symptoms is consistent with two previous longitudinal RT studies [7, 24] and suggests that these symptoms require systematic assessment and management in patients who undergo RT.
Positive_regulation (undergo) of RT
1) Confidence 0.40 Published 2009 Journal Support Care Cancer Section Body Doc Link PMC2762051 Disease Relevance 0.76 Pain Relevance 0.17
Given the paucity of research on changes in symptom clusters over time, the purposes of this study, in a sample of patients who underwent RT, were to determine the occurrence and severity of symptoms at the middle, end, and 1 month after the completion of RT, to determine the number and types of symptom clusters at these three time points, and to evaluate for changes over time in these symptom clusters.


Positive_regulation (underwent) of RT
2) Confidence 0.40 Published 2009 Journal Support Care Cancer Section Body Doc Link PMC2762051 Disease Relevance 0.41 Pain Relevance 0.07
In a study of patients who underwent RT for brain metastasis [7], three symptom clusters were identified at five different time points during RT.
Positive_regulation (underwent) of RT in brain associated with metastasis
3) Confidence 0.40 Published 2009 Journal Support Care Cancer Section Body Doc Link PMC2762051 Disease Relevance 0.36 Pain Relevance 0
Taken together, these findings suggest that future studies of symptom clusters in patients undergoing RT may need to be done within cancer diagnoses to better determine treatment-related symptom clusters.
Positive_regulation (undergoing) of RT associated with cancer
4) Confidence 0.40 Published 2009 Journal Support Care Cancer Section Body Doc Link PMC2762051 Disease Relevance 1.22 Pain Relevance 0.18
Image quality as defined by endocardium border detection was better with 2D than with RT-3D (Figure 3) leading to higher number of uninterpretable segments with RT-3D (18 segments for RT3D vs 7 segments for 2D).
Positive_regulation (leading) of RT-3D in endocardium
5) Confidence 0.40 Published 2008 Journal Cardiovasc Ultrasound Section Body Doc Link PMC2474587 Disease Relevance 0.40 Pain Relevance 0.22
We expected an increase in RT from Set-1 till Set-3 because of the systematically adding of an extra rotational axis, thereby increasing the task difficulty.
Positive_regulation (increase) of RT
6) Confidence 0.15 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0
However, we showed a mental rotation process for Set-1 stimuli (Fig. 2), which was evident from the increase in RT with increasing angle of rotation.
Positive_regulation (increase) of RT
7) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.14 Pain Relevance 0.18
The Set effect was accounted for by the increase in RT for increasing number of axes of rotation, 848 ms, 1,123 ms, and 1,214 ms for Set-1, Set-2, and Set-3, respectively.
Positive_regulation (increase) of RT
8) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0
It might be possible that, because of the dimensionality differences between the frameworks, the complexity increase is largest from Set-1 to Set-2, thereby introducing a larger overall increase in RT.
Positive_regulation (increase) of RT
9) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0.21
According to the low error rates in all sets, which are well below chance level and the increasing RT in all sets for increasing angle of rotation (see Fig. 2), we may assume that participants did indeed mentally rotate the stimuli and were able to solve the mental rotation task accurately (Shepard and Metzler 1971; Sekiyama 1987; Parsons 1994; Helmich et al. 2007).
Positive_regulation (increasing) of RT
10) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.09 Pain Relevance 0.14
In order to support our hypothesis about increasing difference in RT between laterally and medially rotated stimuli, we expected a significant interaction between Set and direction of rotation (DOR).
Positive_regulation (increasing) of RT
11) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0
The DOR effect was accounted for by the increased RT for laterally rotated stimuli (1,117 ms) compared to medially rotated stimuli (1,006 ms).
Positive_regulation (increased) of RT
12) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0
Their results showed that RTs for both groups of children were subject to biomechanical constraints, as evident by the increased RT for difficult hand postures when compared to hand postures that are easier to adopt.
Positive_regulation (increased) of RT
13) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.51 Pain Relevance 0.23
Typically, observed reaction time (RT) profiles show an increase in RT for increased angle of rotation indicating that participants mentally rotate stimuli to the upward position (Shepard and Metzler 1971; Parsons 1994; Jeannerod and Decety 1995).
Positive_regulation (increase) of RT
14) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.15 Pain Relevance 0
Ad hoc analysis revealed a significant increase in RT with increasing angle of rotation for all three sets.
Positive_regulation (increase) of RT
15) Confidence 0.13 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0
We showed increased RT differences between laterally and medially rotated hand stimuli (e.g., direction of rotation (DOR) effect) with increasing number of axes of rotation (see Fig. 3).
Positive_regulation (increased) of RT
16) Confidence 0.09 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.07 Pain Relevance 0.12
Thus, there is an increasing influence of biomechanical constraints on RT with increasing number of axes of rotation, which exemplifies increased engagement in MI (Parsons 1994; Lust et al. 2006).
Positive_regulation (increasing) of RT associated with imagery
17) Confidence 0.09 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.07 Pain Relevance 0.12
A significant effect for Angle with increasing RT with increased angle of rotation would indicate the use of mental rotation (Shepard and Metzler 1971).
Positive_regulation (increasing) of RT
18) Confidence 0.09 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0 Pain Relevance 0.03
More specifically, for 1 axis of rotation, we expected to find no or marginal engagement in MI which will be evidenced by a marginal difference in RT between medial and lateral rotation, whereas increasing engagement in MI (i.e., increasing difference in RT between lateral- and medial-rotated hand pictures) is expected in the conditions with 2- and 3 axes of rotation.


Positive_regulation (increasing) of RT in lateral associated with imagery
19) Confidence 0.09 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.15 Pain Relevance 0.10
More specifically, combined use of palm and back view stimuli increases differences in RT between lateral and medial rotation compared to only presenting back view stimuli, implying a facilitated engagement in MI.
Positive_regulation (increases) of RT in medial associated with imagery
20) Confidence 0.09 Published 2010 Journal Exp Brain Res Section Body Doc Link PMC2871105 Disease Relevance 0.30 Pain Relevance 0.23

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