INT239861

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2010
Negated 1
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 1.32
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (Itga2) plasma membrane (Itga2) nucleus (Itga2)
Anatomy Link Frequency
lymphocytes 1
NK cells 1
platelet 1
T cells 1
Itga2 (Mus musculus)
Pain Link Frequency Relevance Heat
Catecholamine 2 91.36 High High
cytokine 83 81.64 Quite High
Inflammation 55 80.08 Quite High
endometriosis 1 75.40 Quite High
chemokine 25 50.00 Quite Low
depression 3 31.76 Quite Low
Versed 6 30.56 Quite Low
Kinase C 2 27.64 Quite Low
lidocaine 1 20.92 Low Low
Immobilon 1 12.88 Low Low
Disease Link Frequency Relevance Heat
Adhesions 7 100.00 Very High Very High Very High
Cystitis 70 98.96 Very High Very High Very High
INFLAMMATION 64 80.08 Quite High
Endometriosis (extended) 1 75.40 Quite High
Bacteremia 2 71.80 Quite High
Pneumonia 2 70.24 Quite High
Bacterial Infection 2 63.96 Quite High
Infection 159 62.72 Quite High
Pressure And Volume Under Development 5 62.68 Quite High
Leukocytosis 2 53.00 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cells were stained for DX5 and CD3 prior to quantifying by flow cytometry by comparison to a known quantity of CountBright Absolute counting beads (Molecular Probes, Invitrogen, USA) on a Cyan ADP LX 9 color flow cytometer (DAKO, UK).
Gene_expression (stained) of DX5
1) Confidence 0.65 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2827540 Disease Relevance 0 Pain Relevance 0
NK cells were defined as DX5+CD3?
Gene_expression (defined) of DX5 in NK cells
2) Confidence 0.65 Published 2010 Journal PLoS ONE Section Body Doc Link PMC2887844 Disease Relevance 0.06 Pain Relevance 0
In general, the distribution of CD3+CD8+, DX-5+, and CD11b+ lymphocytes changed little after CYP-induced cystitis.
Neg (little) Gene_expression (changed) of DX-5 in lymphocytes associated with cystitis
3) Confidence 0.38 Published 2008 Journal J Immune Based Ther Vaccines Section Body Doc Link PMC2583981 Disease Relevance 0.57 Pain Relevance 0.10
In addition, leptin promotes the expression of adhesion molecules in CD4+ T cells, such as VLA-2 (CD49b) or ICAM-1 (CD54) [5, 18].
Gene_expression (expression) of CD49b in T cells associated with adhesions
4) Confidence 0.12 Published 2010 Journal Mediators of Inflammation Section Body Doc Link PMC2846344 Disease Relevance 0.29 Pain Relevance 0.08
As reported by Chen and colleagues [35], HES 130/0.4 (VoluvenĀ®, which is routinely used in our ICU, induced transient reduction in platelet-mediated coagulation reflected by decreased platelet membrane glycoprotein and P-selectin expression in patients undergoing elective minor surgery.
Gene_expression (expression) of platelet membrane glycoprotein in platelet
5) Confidence 0.05 Published 2008 Journal Crit Care Section Body Doc Link PMC2481479 Disease Relevance 0.40 Pain Relevance 0.14

General Comments

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