INT240061

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Context Info
Confidence 0.44
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 3
Disease Relevance 1.05
Pain Relevance 0.37

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Anatomy Link Frequency
hip 1
muscle 1
brain 1
LRCH1 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 33 96.68 Very High Very High Very High
Glutamate 6 59.92 Quite High
Dopamine 16 54.00 Quite High
Glutamate receptor 2 51.52 Quite High
agonist 2 50.00 Quite Low
cerebral cortex 2 34.40 Quite Low
addiction 60 5.00 Very Low Very Low Very Low
opiate 32 5.00 Very Low Very Low Very Low
alcohol 30 5.00 Very Low Very Low Very Low
Nicotine 26 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Knee Osteoarthritis 31 96.68 Very High Very High Very High
Schizophrenia 78 89.52 High High
Osteoarthritis 2 15.36 Low Low
Post-traumatic Stress Disorder 36 5.00 Very Low Very Low Very Low
Opiate Addiction 26 5.00 Very Low Very Low Very Low
Nicotine Addiction 22 5.00 Very Low Very Low Very Low
Anxiety Disorder 18 5.00 Very Low Very Low Very Low
Alcohol Addiction 18 5.00 Very Low Very Low Very Low
Psychosis 14 5.00 Very Low Very Low Very Low
Disease 10 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The association of LRCH1 in European [14] has not been replicated in Asian [15] patients, and the association for CALM1 identified in Japanese hip OA [16] has not been detected in UK Caucasian patients [17].
LRCH1 Binding (association) of in hip associated with osteoarthritis
1) Confidence 0.44 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483443 Disease Relevance 0.42 Pain Relevance 0.21
Dystrobrevin binding protein 1 (DTNBP1) is a neuronal protein that binds to alpha- and beta-dystrobrevin in muscle and brain [1].
neuronal protein Binding (binds) of in brain
2) Confidence 0.01 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2911395 Disease Relevance 0.32 Pain Relevance 0.08
Dystrobrevin binding protein 1 (DTNBP1) is a neuronal protein that binds to alpha- and beta-dystrobrevin in muscle and brain [1].
neuronal protein Binding (binds) of in muscle
3) Confidence 0.00 Published 2010 Journal Behav Brain Funct Section Body Doc Link PMC2911395 Disease Relevance 0.32 Pain Relevance 0.08

General Comments

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