INT240069

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Context Info
Confidence 0.25
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.75
Pain Relevance 0.59

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (KCNIP3, PDYN) Golgi apparatus (KCNIP3) endoplasmic reticulum (KCNIP3)
DNA binding (KCNIP3) cytoplasm (KCNIP3) cytosol (KCNIP3)
KCNIP3 (Homo sapiens)
PDYN (Homo sapiens)
Pain Link Frequency Relevance Heat
Pain 23 97.32 Very High Very High Very High
Spinal cord 4 96.04 Very High Very High Very High
Osteoarthritis 28 88.24 High High
Pain score 1 70.52 Quite High
Pain management 3 50.00 Quite Low
Lasting pain 12 5.00 Very Low Very Low Very Low
Dynorphin 10 5.00 Very Low Very Low Very Low
Kappa opioid receptor 8 5.00 Very Low Very Low Very Low
Opioid 4 5.00 Very Low Very Low Very Low
antagonist 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Pain 38 97.32 Very High Very High Very High
Frailty 29 88.24 High High
Arthritis 5 50.00 Quite Low
Repression 5 5.00 Very Low Very Low Very Low
Nociception 3 5.00 Very Low Very Low Very Low
Targeted Disruption 2 5.00 Very Low Very Low Very Low
Injury 2 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low
Alzheimer's Dementia 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
To inhibit the blocking function of the DREAM protein on pdyn gene expression in SFLCs, five T7 siRNAs were designed and tested (Figure 3a).
DREAM protein Regulation (function) of Gene_expression (expression) of pdyn
1) Confidence 0.25 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483451 Disease Relevance 0.75 Pain Relevance 0.59

General Comments

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