INT240090

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Context Info
Confidence 0.43
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.30
Pain Relevance 0.06

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (KCNIP3) signal transduction (KCNIP3) Golgi apparatus (KCNIP3)
endoplasmic reticulum (KCNIP3) plasma membrane (KCNIP3) nucleus (KCNIP3)
KCNIP3 (Homo sapiens)
Pain Link Frequency Relevance Heat
Osteoarthritis 28 71.92 Quite High
Pain 23 50.00 Quite Low
Pain management 3 50.00 Quite Low
Opioid 4 30.24 Quite Low
analgesia 1 26.64 Quite Low
Enkephalin 1 20.32 Low Low
Dynorphin 10 19.04 Low Low
Inflammation 1 15.12 Low Low
Lasting pain 12 5.00 Very Low Very Low Very Low
Kappa opioid receptor 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 89.12 High High
Repression 5 85.04 High High
Frailty 29 71.92 Quite High
Pain 38 50.00 Quite Low
Arthritis 5 50.00 Quite Low
Injury 2 16.24 Low Low
INFLAMMATION 1 15.12 Low Low
Nociception 3 5.00 Very Low Very Low Very Low
Hyperalgesia 1 5.00 Very Low Very Low Very Low
Death 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We observed minor variations in c-fos expression levels, which could not be attributed to the suppression of DREAM mRNA since the relative expression of c-fos in other non-DREAM siRNA-transfected SFLCs showed similar fluctuations.
Neg (not) Positive_regulation (attributed) of Negative_regulation (suppression) of DREAM
1) Confidence 0.43 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483451 Disease Relevance 0.30 Pain Relevance 0.06

General Comments

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