INT240123

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.57
Pain Relevance 0.96

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (IL1B) signal transduction (IL1B) extracellular space (IL1B)
aging (IL1B) extracellular region (IL1B) cell-cell signaling (IL1B)
MIR885 (Homo sapiens)
IL1B (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 38 98.64 Very High Very High Very High
rheumatoid arthritis 78 96.40 Very High Very High Very High
anakinra 18 82.68 Quite High
cytokine 14 79.96 Quite High
methotrexate 14 74.56 Quite High
Rheumatism 4 45.04 Quite Low
antagonist 6 39.92 Quite Low
Onset of action 6 25.00 Low Low
Arthritis 12 15.68 Low Low
headache 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Arthritis 28 99.12 Very High Very High Very High
Rheumatoid Arthritis 78 96.40 Very High Very High Very High
Fever 4 83.32 Quite High
INFLAMMATION 26 82.72 Quite High
Disease 20 56.08 Quite High
Rheumatic Diseases 4 45.04 Quite Low
Cancer 4 36.32 Quite Low
Necrosis 4 35.76 Quite Low
Pressure And Volume Under Development 4 5.00 Very Low Very Low Very Low
Headache 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
, and it was demonstrated that ACZ885 can completely suppress IL-1?
ACZ885 Negative_regulation (suppress) of IL-1
1) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Abstract Doc Link PMC2483458 Disease Relevance 0.86 Pain Relevance 0.46
ACZ885 was found to inhibit IL-1?
ACZ885 Negative_regulation (inhibit) of IL-1
2) Confidence 0.01 Published 2008 Journal Arthritis Res Ther Section Body Doc Link PMC2483458 Disease Relevance 0.71 Pain Relevance 0.50

General Comments

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