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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.13
Pain Relevance 0.52

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RBX1) extracellular region (BDNF) cytoplasmic membrane-bounded vesicle (BDNF)
nucleus (RBX1) ligase activity (RBX1) cytoplasm (RBX1)
Anatomy Link Frequency
RBX1 (Homo sapiens)
BDNF (Homo sapiens)
Pain Link Frequency Relevance Heat
Desipramine 12 99.80 Very High Very High Very High
fluoxetine 11 92.80 High High
Serotonin 2 86.60 High High
antidepressant 29 74.32 Quite High
depression 3 65.68 Quite High
Hippocampus 1 61.84 Quite High
sSRI 1 5.00 Very Low Very Low Very Low
tricyclic antidepressant 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 3 67.20 Quite High
Depression 3 65.68 Quite High
Neuroblastoma 6 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The present results suggest that early reduction of total BDNF mRNA in SH-SY5Y cells was mainly accounted for by a reduction of BDNF IV by RBX and DMI administration, and of BDNF VIa/b by RBX.
RBX Negative_regulation (reduction) of BDNF IV in SH-SY5Y associated with desipramine
1) Confidence 0.08 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2483719 Disease Relevance 0.13 Pain Relevance 0.52

General Comments

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