INT24020

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Context Info
Confidence 0.44
First Reported 1987
Last Reported 2010
Negated 0
Speculated 1
Reported most in Body
Documents 6
Total Number 7
Disease Relevance 6.14
Pain Relevance 1.08

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

pigmentation (HPS1) cytoplasmic membrane-bounded vesicle (HPS1) lysosome (HPS1)
cytoplasm (HPS1)
Anatomy Link Frequency
blood 1
HPS1 (Homo sapiens)
Pain Link Frequency Relevance Heat
reflex sympathetic dystrophy 3 100.00 Very High Very High Very High
imagery 2 100.00 Very High Very High Very High
Inflammation 1 99.72 Very High Very High Very High
Pain 3 98.76 Very High Very High Very High
Perioperative pain 2 95.24 Very High Very High Very High
Opioid 2 80.48 Quite High
Neurotransmitter 1 74.08 Quite High
Hippocampus 3 64.16 Quite High
tetrodotoxin 1 61.20 Quite High
noradrenaline 1 46.72 Quite Low
Disease Link Frequency Relevance Heat
Hantavirus Infection 81 100.00 Very High Very High Very High
Complex Regional Pain Syndromes 8 100.00 Very High Very High Very High
Dystonia 6 99.76 Very High Very High Very High
INFLAMMATION 1 99.72 Very High Very High Very High
Infection 26 99.68 Very High Very High Very High
Pain 2 98.76 Very High Very High Very High
Polyps 35 97.60 Very High Very High Very High
Syndrome 42 97.48 Very High Very High Very High
Hyperplasia 15 97.32 Very High Very High Very High
Disease 4 97.04 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
There has been an increase in the use of Human Patient Simulator (HPS) for teaching advanced courses in pharmacology to medical students, residents, and nurses.
Positive_regulation (increase) of HPS associated with hantavirus infection
1) Confidence 0.44 Published 2010 Journal J Opioid Manag Section Abstract Doc Link 20481177 Disease Relevance 0.38 Pain Relevance 0.43
The HPs are likely to be caused by an increase in potassium conductance; their reversal potential was 15-20 mV negative to rest, the reversal potential shifted in the depolarizing direction when the slice was bathed in high potassium medium, and it was the same with KCl or potassium acetate recording electrodes.
Spec (likely) Positive_regulation (caused) of HPs
2) Confidence 0.40 Published 1987 Journal Brain Res. Section Abstract Doc Link 2441803 Disease Relevance 0 Pain Relevance 0.13
While HPS is caused by different hantaviruses in the two regions, the pattern of persistent pulmonary function abnormalities, expiratory flow reduction, and increased residual volume was similar in both groups, likely due to the common pathogenetic features of HPS seen throughout the Americas.
Positive_regulation (caused) of HPS associated with congenital anomalies and hantavirus infection
3) Confidence 0.40 Published 2010 Journal Lung Section Body Doc Link PMC2939327 Disease Relevance 1.09 Pain Relevance 0
HPS is caused by New World hantaviruses that have been identified since the syndrome was first recognized in the southwestern United States in 1993 (2).
Positive_regulation (caused) of HPS associated with syndrome and hantavirus infection
4) Confidence 0.26 Published 2002 Journal Emerging Infectious Diseases Section Body Doc Link PMC2730342 Disease Relevance 1.38 Pain Relevance 0
Cerebral activation during motor imagery in complex regional pain syndrome type 1 with dystonia.
Positive_regulation (activation) of complex regional pain syndrome type 1 associated with complex regional pain syndromes, reflex sympathetic dystrophy, dystonia and imagery
5) Confidence 0.12 Published 2008 Journal Pain Section Title Doc Link 17561345 Disease Relevance 1.03 Pain Relevance 0.29
BACKGROUND: In complex regional pain syndrome type 1 (CRPS1) vascular changes occur from the initial, inflammatory event onto the trophic signs during chronicity of the disease, resulting in blood flow disturbances and marked temperature changes.
Positive_regulation (occur) of complex regional pain syndrome type 1 in blood associated with complex regional pain syndromes, inflammation, reflex sympathetic dystrophy and disease
6) Confidence 0.07 Published 2008 Journal Clin J Pain Section Abstract Doc Link 18180642 Disease Relevance 0.37 Pain Relevance 0.22
The precise molecular mechanism that underlies HPS has not currently been determined.
Positive_regulation (underlies) of HPS associated with hantavirus infection
7) Confidence 0.05 Published 2008 Journal Current Genomics Section Body Doc Link PMC2674304 Disease Relevance 1.89 Pain Relevance 0

General Comments

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