INT240206

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Context Info
Confidence 0.08
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0.51

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (RBX1) nucleus (RBX1) ligase activity (RBX1)
cytoplasm (RBX1)
RBX1 (Homo sapiens)
Pain Link Frequency Relevance Heat
tricyclic antidepressant 1 99.60 Very High Very High Very High
fluoxetine 11 99.18 Very High Very High Very High
sSRI 1 98.86 Very High Very High Very High
Desipramine 12 98.60 Very High Very High Very High
antidepressant 29 97.98 Very High Very High Very High
depression 3 5.00 Very Low Very Low Very Low
Serotonin 2 5.00 Very Low Very Low Very Low
Hippocampus 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 6 75.88 Quite High
Stress 3 29.64 Quite Low
Depression 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Cells were treated for 6, 24 and 48 hours before harvesting (all cells were kept in culture for 3 days total) with different antidepressants: the selective serotonin reuptake inhibitor fluoxetine (FLX), the selective norepinephrine reuptake inhibitor reboxetine (RBX) and the tricyclic antidepressant desipramine (DMI), predominantly inhibiting norepinephrine reuptake (all 10 ?
Negative_regulation (inhibitor) of RBX associated with desipramine, antidepressant, tricyclic antidepressant, ssri and fluoxetine
1) Confidence 0.08 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2483719 Disease Relevance 0.15 Pain Relevance 0.51

General Comments

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