INT240207

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Context Info
Confidence 0.45
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0.32
Pain Relevance 1.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (BDNF) cytoplasmic membrane-bounded vesicle (BDNF)
Anatomy Link Frequency
brain 2
BDNF (Homo sapiens)
Pain Link Frequency Relevance Heat
antidepressant 87 99.84 Very High Very High Very High
Desipramine 36 97.36 Very High Very High Very High
fluoxetine 33 88.76 High High
Serotonin 6 82.56 Quite High
depression 9 81.12 Quite High
Hippocampus 3 77.28 Quite High
sSRI 3 5.00 Very Low Very Low Very Low
tricyclic antidepressant 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Stress 9 82.64 Quite High
Depression 9 81.12 Quite High
Neuroblastoma 18 50.00 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
On the other hand, the increase in total BDNF mRNA after 48 hours of treatment appeared to be mainly accounted for by the induction of BDNF IV by both drugs.
Regulation (accounted) of Positive_regulation (induction) of BDNF IV
1) Confidence 0.45 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2483719 Disease Relevance 0.16 Pain Relevance 0.48
On the other hand, the increase in total BDNF mRNA after 48 hours of treatment appeared to be mainly accounted for by the induction of BDNF IV by both drugs.
Regulation (accounted) of Positive_regulation (increase) of BDNF mRNA
2) Confidence 0.39 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2483719 Disease Relevance 0.16 Pain Relevance 0.50
Previous studies found time-dependent biphasic changes in the expression of total BDNF induced by antidepressants in rat brain [4-6].
Regulation (changes) of Positive_regulation (induced) of BDNF in brain associated with antidepressant
3) Confidence 0.24 Published 2008 Journal BMC Neurosci Section Body Doc Link PMC2483719 Disease Relevance 0 Pain Relevance 0.39

General Comments

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