INT240271

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Context Info
Confidence 0.09
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.04
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (GDNF, RET) endosome (RET) extracellular region (GDNF)
plasma membrane (RET)
GDNF (Homo sapiens)
RET (Homo sapiens)
Pain Link Frequency Relevance Heat
Enkephalin 2 9.28 Low Low
Opioid 2 5.00 Very Low Very Low Very Low
imagery 2 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
opioid receptor 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 128 98.28 Very High Very High Very High
Lung Cancer 54 97.64 Very High Very High Very High
Pancreatic Cancer 2 96.12 Very High Very High Very High
Diabetes Mellitus 1 86.28 High High
Reprotox - General 1 4 77.60 Quite High
Recurrence 1 76.20 Quite High
Breast Cancer 2 71.20 Quite High
Leukemia 2 70.40 Quite High
Skin Cancer 26 41.44 Quite Low
Death 3 32.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
As a ligand for the RET proto-oncogene, GDNF would be a likely candidate for promoting cancer progression, and has been proposed to do so in pancreatic cancer [55].
GDNF Binding (ligand) of RET proto-oncogene associated with cancer and pancreatic cancer
1) Confidence 0.09 Published 2008 Journal Mol Cancer Section Body Doc Link PMC2483990 Disease Relevance 1.04 Pain Relevance 0

General Comments

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