INT240614

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Context Info
Confidence 0.38
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 5
Total Number 5
Disease Relevance 6.10
Pain Relevance 0.99

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Etv3) DNA binding (Etv3)
Anatomy Link Frequency
Heart 1
Etv3 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 68 99.04 Very High Very High Very High
Kinase C 18 90.88 High High
cytokine 6 80.08 Quite High
ischemia 1 54.08 Quite High
Angina 2 49.48 Quite Low
tolerance 7 5.00 Very Low Very Low Very Low
alcohol 6 5.00 Very Low Very Low Very Low
Inflammatory marker 4 5.00 Very Low Very Low Very Low
corticosteroid 2 5.00 Very Low Very Low Very Low
fibrosis 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Metabolic Syndrome 153 100.00 Very High Very High Very High
Insulin Resistance 50 100.00 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

12 99.90 Very High Very High Very High
Fatty Liver 11 99.58 Very High Very High Very High
INFLAMMATION 75 99.04 Very High Very High Very High
Obesity 145 98.92 Very High Very High Very High
Disorder Of Lipid Metabolism 122 95.10 Very High Very High Very High
Endometriosis (extended) 4 93.08 High High
Diabetes Mellitus 31 90.24 High High
Hyperglycemia 3 89.68 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NAFLD markers ALT and AST predict MetS independently of potential confounding variables [38].
Gene_expression (predict) of MetS associated with fatty liver and metabolic syndrome
1) Confidence 0.38 Published 2010 Journal Journal of Clinical Biochemistry and Nutrition Section Body Doc Link PMC2872226 Disease Relevance 1.50 Pain Relevance 0.03
Lifestyle modifications including diet and exercise are recommended as first-line intervention for treating insulin resistance and MetS by the National Cholesterol Education Program (NCEP) and American Heart Association (AHA).
Gene_expression (resistance) of MetS in Heart associated with metabolic syndrome and insulin resistance
2) Confidence 0.27 Published 2008 Journal Nutr Metab (Lond) Section Body Doc Link PMC2588603 Disease Relevance 1.42 Pain Relevance 0.40
Hence, therapies which reduce circulating lipids and reduce systemic inflammation have shown promise in the treatment of insulin resistance and MetS.
Gene_expression (resistance) of MetS associated with inflammation, metabolic syndrome and insulin resistance
3) Confidence 0.24 Published 2008 Journal Nutr Metab (Lond) Section Body Doc Link PMC2588603 Disease Relevance 1.38 Pain Relevance 0.43
The study's large sample size, being based on a
    representative sample of a general population of both sexes, in which MetS prevailed highly,
    the range of obesity measures were wide, adjustments were made for such parameters as insulin,
    CRP, apo B and SHBG and validity shown also exclusively in menopausal women constitute
    strengths of the study. 
Gene_expression (prevailed) of MetS associated with endometriosis (extended) and obesity
4) Confidence 0.06 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2491727 Disease Relevance 0.82 Pain Relevance 0.10
Thus, the aim of this study was to evaluate: 1) the nature and linearity of the association
   between different indicators of obesity and serum adiponectin levels, 2) whether or not
   anticipated inverse associations between adiponectin and HDL-cholesterol, triglycerides/apo B
   and CRP exist independent of BMI or waist circumference, 3) whether SHBG plays an independent
   role on concentrations of adiponectin in Turkish men and women in whom both atherogenic
   dyslipidemia and MetS prevail 11.


Gene_expression (prevail) of MetS associated with obesity and disorder of lipid metabolism
5) Confidence 0.06 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2491727 Disease Relevance 0.75 Pain Relevance 0.03

General Comments

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