INT240617

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Context Info
Confidence 0.04
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 3.62
Pain Relevance 0.38

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (APOB, ADIPOQ) extracellular space (APOB, ADIPOQ) extracellular region (APOB, ADIPOQ)
transport (APOB) small molecule metabolic process (APOB) enzyme binding (APOB)
APOB (Homo sapiens)
ADIPOQ (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 60 84.68 Quite High
chemokine 3 80.28 Quite High
Angina 3 60.88 Quite High
cytokine 3 14.60 Low Low
Inflammatory marker 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 54 100.00 Very High Very High Very High
Obesity 168 98.64 Very High Very High Very High
Metabolic Syndrome 18 96.04 Very High Very High Very High
Dyslipidemia /

Combined Dyslipidemia

12 92.20 High High
Insulin Resistance 15 87.60 High High
Endometriosis (extended) 6 85.88 High High
INFLAMMATION 69 84.68 Quite High
Adhesions 3 81.64 Quite High
Diabetes Mellitus 9 66.72 Quite High
Hyperlipidemia 3 63.52 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Adiponectin failed to be linked with
    CRP and HDL and was positively associated with apo B in women, contrasted to men. 
apo B Binding (associated) of Adiponectin associated with disorder of lipid metabolism
1) Confidence 0.04 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2491727 Disease Relevance 0.87 Pain Relevance 0.10
Impaired interaction with one of the known or unknown adiponectin receptors enhanced by low
    SHBG might be hypothesized as an underlying mechanism, perhaps with resulting interaction
    between adiponectin and apo B. 
apo B Binding (interaction) of adiponectin
2) Confidence 0.03 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2491727 Disease Relevance 1.40 Pain Relevance 0.19
Thus, the aim of this study was to evaluate: 1) the nature and linearity of the association
   between different indicators of obesity and serum adiponectin levels, 2) whether or not
   anticipated inverse associations between adiponectin and HDL-cholesterol, triglycerides/apo B
   and CRP exist independent of BMI or waist circumference, 3) whether SHBG plays an independent
   role on concentrations of adiponectin in Turkish men and women in whom both atherogenic
   dyslipidemia and MetS prevail 11.


apo B Neg (not) Binding (associations) of adiponectin associated with obesity and disorder of lipid metabolism
3) Confidence 0.03 Published 2008 Journal International Journal of Biological Sciences Section Body Doc Link PMC2491727 Disease Relevance 1.03 Pain Relevance 0.09

General Comments

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