INT240877

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 1
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.20
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Ros1) cell proliferation (Ros1) extracellular space (Ins1)
signal transduction (Ros1) extracellular region (Ins1) plasma membrane (Ros1)
Ros1 (Mus musculus)
Ins1 (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 11 81.88 Quite High
cytokine 2 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 10 81.88 Quite High
Diabetes Mellitus 6 55.24 Quite High
Stress 3 50.00 Quite Low
Weight Gain 1 38.92 Quite Low
Body Weight 4 30.64 Quite Low
Insulin Resistance 21 5.00 Very Low Very Low Very Low
Obesity 2 5.00 Very Low Very Low Very Low
Hyperglycemia 2 5.00 Very Low Very Low Very Low
Adenovirus Infection 1 5.00 Very Low Very Low Very Low
Disease 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Whereas previous studies showed that Akt reduced transactivation of Foxo1 through the phosphorylation of Foxo1 at Ser256 (37,38), our data demonstrated that the phosphorylation of Foxo1 at Ser256 was augmented by reduction of ROS independently of the insulin signal at Akt phosphorylation level.
Negative_regulation (reduction) of ROS Neg (independently) Positive_regulation (augmented) of Phosphorylation (phosphorylation) of insulin
1) Confidence 0.03 Published 2008 Journal Diabetes Section Body Doc Link PMC2494675 Disease Relevance 0.20 Pain Relevance 0.07

General Comments

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