INT240895

Context Info Confidence 0.12 First Reported 2008 Last Reported 2008 Negated 0 Speculated 0 Reported most in Body Documents 1 Total Number 2 Disease Relevance 0.17 Pain Relevance 0

mitochondrion (Mapk14, Creb1) nucleus (Mapk14, Creb1) cell morphogenesis (Mapk14) DNA binding (Creb1) response to stress (Mapk14) cytoplasm (Mapk14)

Anatomy Link Frequency liver 3 hepatocytes 1 Mapk14 (Mus musculus) Creb1 (Mus musculus)

Pain Link Frequency Relevance Heat tolerance 22 5.00 cytokine 4 5.00 anesthesia 2 5.00

Disease Link Frequency Relevance Heat Insulin Resistance 42 86.80 Stress 6 50.00 Diabetes Mellitus 12 5.84 Impaired Glucose Tolerance 20 5.00 Body Weight 8 5.00 Obesity 4 5.00 Hyperglycemia 4 5.00 Adenovirus Infection 2 5.00 Disease 2 5.00 Weight Gain 2 5.00

Sentences Mentioned In

Key:

Protein

Mutation

Event

Anatomy

Negation

Speculation

Pain term

Disease term

In addition, ERK and p38 MAPK regulate the phosphorylation of CREB in hepatocytes and liver (27–29).

p38 Regulation (regulate) of Phosphorylation (phosphorylation) of CREB in liver

1) Confidence 0.12 Published 2008 Journal Diabetes Section Body Doc Link PMC2494675 Disease Relevance 0.09 Pain Relevance 0

In addition, ERK and p38 MAPK regulate the phosphorylation of CREB in hepatocytes and liver (27–29).

p38 Regulation (regulate) of in hepatocytes Phosphorylation (phosphorylation) of CREB in liver

2) Confidence 0.04 Published 2008 Journal Diabetes Section Body Doc Link PMC2494675 Disease Relevance 0.09 Pain Relevance 0

General Comments

This test has worked.