INT240921

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.12
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endoplasmic reticulum (G6pc)
G6pc (Mus musculus)
Pain Link Frequency Relevance Heat
tolerance 8 15.16 Low Low
agonist 1 5.00 Very Low Very Low Very Low
Kinase C 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Immobilon 1 5.00 Very Low Very Low Very Low
imagery 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disorder Of Lipid Metabolism 3 63.68 Quite High
Diabetes Mellitus 20 56.00 Quite High
Dyslipidemia /

Combined Dyslipidemia

1 50.00 Quite Low
Obesity 8 37.60 Quite Low
Insulin Resistance 12 29.04 Quite Low
Fatty Liver 1 27.28 Quite Low
Targeted Disruption 10 5.00 Very Low Very Low Very Low
Impaired Glucose Tolerance 4 5.00 Very Low Very Low Very Low
Lipidosis 3 5.00 Very Low Very Low Very Low
Hyperglycemia 2 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
These data suggest that insulin signaling through AKT-dependent FOXO1 phosphorylation contributes to the observed reduction in steady-state mRNA levels for gluconeogenic genes such as G6pc and Pck1.


Positive_regulation (contributes) of Negative_regulation (reduction) of G6pc
1) Confidence 0.42 Published 2008 Journal Diabetes Section Body Doc Link PMC2494684 Disease Relevance 0.12 Pain Relevance 0

General Comments

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