INT240935

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Context Info
Confidence 0.68
First Reported 2008
Last Reported 2011
Negated 0
Speculated 0
Reported most in Body
Documents 2
Total Number 2
Disease Relevance 0.42
Pain Relevance 0.42

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Sirt1) nucleoplasm (Sirt1) nuclear envelope (Sirt1)
histone binding (Sirt1) enzyme binding (Sirt1) cytoplasm (Sirt1)
Sirt1 (Mus musculus)
Pain Link Frequency Relevance Heat
electroacupuncture 82 97.56 Very High Very High Very High
tolerance 15 75.48 Quite High
Acupuncture 10 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Spinal cord 1 5.00 Very Low Very Low Very Low
anesthesia 1 5.00 Very Low Very Low Very Low
Inflammation 1 5.00 Very Low Very Low Very Low
Pain 1 5.00 Very Low Very Low Very Low
Fibrositis 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Impaired Glucose Tolerance 7 75.48 Quite High
Diabetes Mellitus 34 65.64 Quite High
Targeted Disruption 10 62.76 Quite High
Stress 2 51.80 Quite High
Obesity 20 50.00 Quite Low
Dyslipidemia /

Combined Dyslipidemia

1 50.00 Quite Low
Insulin Resistance 38 5.00 Very Low Very Low Very Low
Hyperglycemia 5 5.00 Very Low Very Low Very Low
Disorder Of Lipid Metabolism 5 5.00 Very Low Very Low Very Low
Lipidosis 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
EA significantly increased SIRT1 protein levels in db/db and db/m mice (Figure 2), but it produced no significant effect on SIRT1 mRNA levels (Figure 3(a)).
Transcription (levels) of SIRT1 associated with electroacupuncture
1) Confidence 0.68 Published 2011 Journal Evidence-based Complementary and Alternative Medicine : eCAM Section Body Doc Link PMC2964507 Disease Relevance 0.13 Pain Relevance 0.42
Moreover, Sirt1 transcription is inhibited by a NADH-mediated mechanism (41).
Transcription (transcription) of Sirt1
2) Confidence 0.42 Published 2008 Journal Diabetes Section Body Doc Link PMC2494684 Disease Relevance 0.29 Pain Relevance 0

General Comments

This test has worked.

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