INT241052

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 0
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nuclear envelope (Tpr) molecular_function (Tpr)
Anatomy Link Frequency
poly 1
NS20Y 1
Tpr (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 33 86.00 High High
Opioid 9 50.00 Quite Low
Central nervous system 3 6.08 Low Low
Morphine 9 5.00 Very Low Very Low Very Low
addiction 6 5.00 Very Low Very Low Very Low
tolerance 6 5.00 Very Low Very Low Very Low
dopamine receptor 3 5.00 Very Low Very Low Very Low
Analgesic 3 5.00 Very Low Very Low Very Low
analgesia 3 5.00 Very Low Very Low Very Low
potassium channel 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Apoptosis 3 39.36 Quite Low
Neuroblastoma 12 5.00 Very Low Very Low Very Low
Hypersensitivity 9 5.00 Very Low Very Low Very Low
Cancer 3 5.00 Very Low Very Low Very Low
Targeted Disruption 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
We have used this new procedure to purify new transcription factors that bind to the poly(C) sequence of the Oprm1 proximal promoter (31).
promoter Binding (bind) of in poly
1) Confidence 0.01 Published 2008 Journal Molecular & Cellular Proteomics : MCP Section Body Doc Link PMC2494908 Disease Relevance 0 Pain Relevance 0.03
Our earlier studies showed that mouse Oprm1 transcription was regulated by a cis-acting single strand DNA sequence that was essential for the activity of the mouse Oprm1 promoter through the binding of ?
promoter Binding (binding) of
2) Confidence 0.01 Published 2008 Journal Molecular & Cellular Proteomics : MCP Section Body Doc Link PMC2494908 Disease Relevance 0 Pain Relevance 0.04
We used affinity column chromatography containing a specific competitor, two-dimensional gel electrophoresis, and mass spectrometry to purify and identify the factors that interact specifically with the single strand DNA from the Oprm1 proximal promoter region of mouse neuronal NS20Y cells.
promoter Binding (interact) of in NS20Y
3) Confidence 0.01 Published 2008 Journal Molecular & Cellular Proteomics : MCP Section Body Doc Link PMC2494908 Disease Relevance 0 Pain Relevance 0.04

General Comments

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