INT241072

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Context Info
Confidence 0.01
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Abstract
Documents 1
Total Number 1
Disease Relevance 0.08
Pain Relevance 0.36

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

signal transduction (Oprm1) nuclear envelope (Tpr) plasma membrane (Oprm1)
molecular_function (Tpr) signal transducer activity (Oprm1)
Anatomy Link Frequency
neuronal 2
Tpr (Mus musculus)
Oprm1 (Mus musculus)
Pain Link Frequency Relevance Heat
opioid receptor 11 99.54 Very High Very High Very High
Morphine 3 93.08 High High
Opioid 3 75.00 Quite High
addiction 2 5.00 Very Low Very Low Very Low
tolerance 2 5.00 Very Low Very Low Very Low
dopamine receptor 1 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Analgesic 1 5.00 Very Low Very Low Very Low
analgesia 1 5.00 Very Low Very Low Very Low
potassium channel 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Neuroblastoma 4 83.76 Quite High
Hypersensitivity 3 5.00 Very Low Very Low Very Low
Cancer 1 5.00 Very Low Very Low Very Low
Apoptosis 1 5.00 Very Low Very Low Very Low
Targeted Disruption 1 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
opioid receptor gene (Oprm1) proximal promoter was found to be important for regulating Oprm1 in neuronal cells.
promoter Positive_regulation (important) of Regulation (regulating) of Oprm1 in neuronal associated with opioid receptor
1) Confidence 0.01 Published 2008 Journal Molecular & Cellular Proteomics : MCP Section Abstract Doc Link PMC2494908 Disease Relevance 0.08 Pain Relevance 0.36

General Comments

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