INT241259

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Context Info
Confidence 0.05
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.68
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (DNMT3B, GOPC) Golgi apparatus (GOPC) nucleolus (DNMT3B)
plasma membrane (GOPC) nucleus (DNMT3B) DNA binding (DNMT3B)
DNMT3B (Homo sapiens)
GOPC (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 2 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Targeted Disruption 2 100.00 Very High Very High Very High
Colon Cancer 1 100.00 Very High Very High Very High
Cancer 56 98.16 Very High Very High Very High
Lymphatic System Cancer 15 86.28 High High
Carcinoma 13 85.76 High High
Prostate Cancer 5 45.28 Quite Low
Ovarian Cancer 4 20.64 Low Low
Nasopharynx Cancer 23 5.00 Very Low Very Low Very Low
Stress 18 5.00 Very Low Very Low Very Low
Adhesions 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
OPCML-v1 could also be induced in the colorectal cancer cell line HCT116 which is completely methylated for this gene, by genetic demethylation through double knock-out of both DNA methyltransferases DNMT1 and DNMT3B (DKO cell line) [25] (Fig. 4B).
DNMT3B Positive_regulation (induced) of Fig associated with targeted disruption and colon cancer
1) Confidence 0.05 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500176 Disease Relevance 0.68 Pain Relevance 0

General Comments

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