INT241297

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Context Info
Confidence 0.62
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 3
Disease Relevance 1.79
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell adhesion (OPCML) plasma membrane (OPCML)
Anatomy Link Frequency
SW480 1
OPCML (Homo sapiens)
Pain Link Frequency Relevance Heat
Opioid 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Cancer 168 97.78 Very High Very High Very High
Stress 54 85.52 High High
Apoptosis 3 80.48 Quite High
Nasopharynx Cancer 69 72.56 Quite High
Esophageal Cancer 9 71.92 Quite High
Adhesions 27 69.84 Quite High
Prostate Cancer 15 61.72 Quite High
Lymphatic System Cancer 45 57.24 Quite High
Carcinoma 39 56.68 Quite High
Ovarian Cancer 12 42.12 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Using primers specific to the common exons of OPCML transcripts, we found the expression of OPCML in several tumor cell lines (Hep3B, H292, SW480, L1236), where the OPCML-v1 and v2 were totally silenced (Fig. 1F), indicating transcription of OPCML from alternative unknown promoters.
Transcription (transcription) of OPCML in SW480 associated with cancer
1) Confidence 0.62 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500176 Disease Relevance 0.22 Pain Relevance 0
In summary, we found that the expression of OPCML-v1 (NM_002545), a major transcript of this TSG, is frequently silenced or down-regulated in multiple tumors.
Transcription (transcript) of OPCML-v1 associated with cancer
2) Confidence 0.60 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500176 Disease Relevance 1.15 Pain Relevance 0
Our results also reveal that OPCML transcripts v1 and v2 have different tissue expression patterns.
Transcription (transcripts) of OPCML
3) Confidence 0.60 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500176 Disease Relevance 0.42 Pain Relevance 0

General Comments

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