INT241390

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.03
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cell differentiation (Epas1) signal transduction (Epas1) mitochondrion organization (Epas1)
nucleus (Epas1) DNA binding (Epas1) transcription factor binding (Epas1)
Epas1 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 21 71.84 Quite High
cytokine 2 63.28 Quite High
cINOD 4 45.96 Quite Low
withdrawal 1 35.44 Quite Low
dexamethasone 52 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 2 99.46 Very High Very High Very High
Solid Tumor 1 99.00 Very High Very High Very High
Carcinoma 1 93.60 High High
Cancer 59 84.40 Quite High
INFLAMMATION 23 71.84 Quite High
Toxicity 8 67.20 Quite High
Cervical Cancer 26 61.84 Quite High
Disease 1 46.16 Quite Low
Infection 10 43.80 Quite Low
Injury 1 43.28 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, bulky solid tumor masses contain hypoxic areas, which feature high levels of the HIF-1 transcription factor, which in turn induces VEGF and Cox-2 expression [23].
Positive_regulation (levels) of HIF-1 transcription factor associated with hypoxia and solid tumor
1) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500220 Disease Relevance 1.03 Pain Relevance 0.07

General Comments

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