INT241400

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Context Info
Confidence 0.03
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 1.09
Pain Relevance 0.07

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytoplasm (Epas1, VEGFA) cell differentiation (Epas1) mitochondrion organization (Epas1)
DNA binding (Epas1) signal transducer activity (Epas1) signal transduction (Epas1)
Epas1 (Mus musculus)
VEGFA (Homo sapiens)
Pain Link Frequency Relevance Heat
Inflammation 21 75.76 Quite High
cytokine 2 62.72 Quite High
cINOD 4 45.40 Quite Low
withdrawal 1 34.88 Quite Low
dexamethasone 52 5.00 Very Low Very Low Very Low
Potency 5 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hypoxia 2 99.18 Very High Very High Very High
Solid Tumor 1 98.72 Very High Very High Very High
Carcinoma 1 93.04 High High
Cancer 59 86.48 High High
INFLAMMATION 23 75.76 Quite High
Toxicity 8 66.64 Quite High
Cervical Cancer 26 65.76 Quite High
Disease 1 50.08 Quite High
Infection 10 43.24 Quite Low
Injury 1 42.72 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Further, bulky solid tumor masses contain hypoxic areas, which feature high levels of the HIF-1 transcription factor, which in turn induces VEGF and Cox-2 expression [23].
HIF-1 transcription factor Positive_regulation (induces) of Gene_expression (expression) of VEGF associated with hypoxia and solid tumor
1) Confidence 0.03 Published 2008 Journal PLoS ONE Section Body Doc Link PMC2500220 Disease Relevance 1.09 Pain Relevance 0.07

General Comments

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