INT24173

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Context Info
Confidence 0.40
First Reported 1987
Last Reported 2007
Negated 0
Speculated 0
Reported most in Abstract
Documents 6
Total Number 6
Disease Relevance 2.69
Pain Relevance 1.81

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (FCGR3A) plasma membrane (FCGR3A)
Anatomy Link Frequency
spinal cord 1
respiratory 1
FCGR3A (Homo sapiens)
Pain Link Frequency Relevance Heat
Spinal cord 6 97.36 Very High Very High Very High
visual analogue scale 8 96.80 Very High Very High Very High
Pain 21 96.40 Very High Very High Very High
Analgesic 1 94.96 High High
c fibre 1 67.60 Quite High
spinoreticular tract 1 64.48 Quite High
spinal dorsal horn 1 59.04 Quite High
wide dynamic range 1 57.52 Quite High
analgesia 2 54.48 Quite High
nociceptor 6 25.00 Low Low
Disease Link Frequency Relevance Heat
Nociception 20 99.20 Very High Very High Very High
Spinal Cord Injury 5 97.36 Very High Very High Very High
Pain 10 95.56 Very High Very High Very High
Dyspnea 6 93.36 High High
Syndrome 3 93.16 High High
Injury 1 50.16 Quite High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
This inhibition of the RIII reflex is absent in tetraplegic patient with clinically complete spinal cord transections and can be triggered only from the analgesic hand in patients with Wallenberg's syndrome.
Negative_regulation (inhibition) of RIII in spinal cord associated with syndrome, analgesic and spinal cord
1) Confidence 0.40 Published 1993 Journal Ann. Neurol. Section Abstract Doc Link 8215241 Disease Relevance 0.57 Pain Relevance 0.39
This led to progressive inhibition of the RIII reflex that reached 50 +/- 12% during the fifth minute of loading (P < 0.001), was correlated to the intensity of the self-evaluated respiratory discomfort, and had recovered 5 min after removal of the load.
Negative_regulation (inhibition) of RIII in respiratory
2) Confidence 0.37 Published 2007 Journal J. Neurophysiol. Section Abstract Doc Link 16870842 Disease Relevance 0.72 Pain Relevance 0.36
In tetraplegic patients not only was the RIII reflex never decreased by the heterotopic nociceptive stimulation but it was, in fact, slightly enhanced.
Negative_regulation (decreased) of RIII associated with nociception
3) Confidence 0.29 Published 1987 Journal Brain Section Abstract Doc Link 2448000 Disease Relevance 0.61 Pain Relevance 0.27
It simultaneously induced a strong inhibition of the RIII reflex which outlasted the conditioning period by several minutes.
Negative_regulation (inhibition) of RIII
4) Confidence 0.29 Published 1987 Journal Brain Section Abstract Doc Link 2448000 Disease Relevance 0.65 Pain Relevance 0.24
Similarly, we found a significantly lower percentage reduction of the RIII area in women than in men during the CPT.
Negative_regulation (reduction) of RIII
5) Confidence 0.17 Published 2004 Journal Pain Section Abstract Doc Link 15561391 Disease Relevance 0.06 Pain Relevance 0.29
In all the subjects, the CPT induced a significant TST increase and RIII area reduction compared with the control session.
Negative_regulation (reduction) of RIII
6) Confidence 0.17 Published 2004 Journal Pain Section Abstract Doc Link 15561391 Disease Relevance 0.08 Pain Relevance 0.26

General Comments

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