INT241774

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.48
Pain Relevance 0.09

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

endosome (AVPR1A) generation of precursor metabolites and energy (AVPR1A) plasma membrane (AVPR1A)
response to stress (AVPR1A) signal transducer activity (AVPR1A)
AVPR1A (Homo sapiens)
TRGV9 (Homo sapiens)
Pain Link Frequency Relevance Heat
antagonist 21 67.44 Quite High
anticonvulsant 2 5.00 Very Low Very Low Very Low
Neuropeptide 2 5.00 Very Low Very Low Very Low
tricyclic antidepressant 2 5.00 Very Low Very Low Very Low
Pain 2 5.00 Very Low Very Low Very Low
Nicotine 1 5.00 Very Low Very Low Very Low
Bioavailability 1 5.00 Very Low Very Low Very Low
Versed 1 5.00 Very Low Very Low Very Low
medulla 1 5.00 Very Low Very Low Very Low
withdrawal 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Hyponatremia 62 77.24 Quite High
Heart Rate Under Development 24 60.48 Quite High
Pressure And Volume Under Development 9 58.80 Quite High
Atherosclerosis 1 57.44 Quite High
Disease 1 56.16 Quite High
Hypotension 1 48.88 Quite Low
Cirrhosis 9 46.96 Quite Low
Hemorrhage 1 31.20 Quite Low
Hypothermia 1 29.28 Quite Low
Increased Venous Pressure Under Development 5 27.36 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Although conivaptan has high affinities for both V1A and V2 receptors, radioligand competition binding assays revealed a tenfold higher affinity for V2 than that for V1A receptors (Burnier et al 1999).
V1A Binding (affinity) of V2
1) Confidence 0.02 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.48 Pain Relevance 0.09

General Comments

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