INT241776

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Context Info
Confidence 0.06
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.54
Pain Relevance 0.32

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

transmembrane transport (AVP, ADCY1) signal transduction (AVP, ADCY1) small molecule metabolic process (ADCY1)
GTPase activity (ADCY1) cell-cell signaling (AVP) response to stress (AVP)
Anatomy Link Frequency
ducts 2
AVP (Homo sapiens)
ADCY1 (Homo sapiens)
Pain Link Frequency Relevance Heat
adenocard 1 98.24 Very High Very High Very High
Pain 2 66.40 Quite High
anticonvulsant 2 62.84 Quite High
tricyclic antidepressant 2 62.16 Quite High
Nicotine 1 60.08 Quite High
Morphine 1 59.68 Quite High
Neuropeptide 2 54.52 Quite High
bradykinin 1 53.80 Quite High
Neurotransmitter 1 48.48 Quite Low
medulla 1 47.04 Quite Low
Disease Link Frequency Relevance Heat
Increased Venous Pressure Under Development 5 92.84 High High
Myocardial Infarction 16 92.00 High High
Pressure And Volume Under Development 9 91.40 High High
Hypoglycemia 1 67.12 Quite High
Pain 2 66.40 Quite High
Vomiting 6 66.16 Quite High
Hyponatremia 62 50.00 Quite Low
Pressure Volume 2 Under Development 12 44.64 Quite Low
Heart Rate Under Development 24 5.00 Very Low Very Low Very Low
Cirrhosis 9 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Binding of circulating AVP to the G-protein-coupled V2 receptors on the basolateral membranes of principal cells in the collecting ducts activates adenylyl cyclase, thereby enhances the production of cyclic adenosine monophosphate (cAMP) and the subsequent activation of protein kinase A.
AVP Binding (Binding) of in ducts Positive_regulation (activates) of adenylyl cyclase associated with adenocard
1) Confidence 0.06 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504060 Disease Relevance 0.54 Pain Relevance 0.32

General Comments

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