INT241788
From wiki-pain
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Sentences Mentioned In
Key: | Protein | Mutation | Event | Anatomy | Negation | Speculation | Pain term | Disease term |
Instead, a 40% increase in the expression of the water channel aquaporin-2 water in the renal collecting duct was shown, suggesting a direct renal effect of the drug. | |||||||||||||||
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The subgroup of aquaporins is composed of AQP0, AQP1, AQP2, AQP4, AQP5, AQP6 and AQP8 and is considered to be mainly permeable to water with a high flow rate. | |||||||||||||||
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The down-stream effect is enhanced production and trafficking of the water channels aquaporin-2 to the luminal membranes to facilitate water reabsorption into the hypertonic medullary interstitium. | |||||||||||||||
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General Comments
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