INT241793

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Context Info
Confidence 0.00
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.83
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

extracellular region (NBL1) Golgi apparatus (B4GALNT1) plasma membrane (B4GALNT1)
carbohydrate metabolic process (B4GALNT1)
NBL1 (Homo sapiens)
B4GALNT1 (Homo sapiens)
Pain Link Frequency Relevance Heat
peripheral neuropathy 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Paresthesia 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Gauchers Disease 31 99.92 Very High Very High Very High
Neurologic Manifestations 4 84.24 Quite High
Disease 3 80.28 Quite High
Fabry Disease 1 73.08 Quite High
Lysosome Storage Disease 3 59.36 Quite High
Neurological Disease 2 33.16 Quite Low
Hypersensitivity 1 5.92 Low Low
Diarrhoea 9 5.00 Very Low Very Low Very Low
Weight Loss 8 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
NB-DNJ (miglustat) is one of the N-alkylated iminosugars extracted from plants and microorganisms, and inhibits glycosylceramide synthase, which catalyzes the transfer of glucose from UDP-glucose to ceramide to form glucosylceramide (GlcCer) (Figure 1).
NB-DNJ Negative_regulation (inhibits) of synthase
1) Confidence 0.00 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504062 Disease Relevance 0.83 Pain Relevance 0

General Comments

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