INT241801

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Context Info
Confidence 0.13
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.15
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

peptidase activity (CTSA) mitochondrion (CTSA) small molecule metabolic process (CTSA)
endoplasmic reticulum (CTSA) nucleolus (CTSA) nucleus (CTSA)
CTSA (Homo sapiens)
Pain Link Frequency Relevance Heat
peripheral neuropathy 6 5.00 Very Low Very Low Very Low
Pain 3 5.00 Very Low Very Low Very Low
Central nervous system 1 5.00 Very Low Very Low Very Low
Paresthesia 1 5.00 Very Low Very Low Very Low
abdominal pain 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Death 2 90.52 High High
Gauchers Disease 31 60.56 Quite High
Virus Diseases 1 49.04 Quite Low
Acquired Immune Deficiency Syndrome Or Hiv Infection 2 47.20 Quite Low
Neurologic Manifestations 4 9.60 Low Low
Disease 3 5.64 Low Low
Diarrhoea 9 5.00 Very Low Very Low Very Low
Weight Loss 8 5.00 Very Low Very Low Very Low
Peripheral Neuropathy 6 5.00 Very Low Very Low Very Low
Tremor 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Several animal studies also showed that depletion of GSL could be lethal or lead to neurological disturbance, and substrate reduction therapy should be aimed to reduce biosynthesis of GSL to a degree that can be tolerated by cells (Radin 1996).
GSL Binding (depletion) of
1) Confidence 0.13 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504062 Disease Relevance 0.15 Pain Relevance 0

General Comments

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