INT241865

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Context Info
Confidence 0.02
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.61
Pain Relevance 0.22

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (SLC40A1) transmembrane transport (SLC40A1) cytoplasm (SLC40A1)
Anatomy Link Frequency
plasma 2
SLC40A1 (Homo sapiens)
Pain Link Frequency Relevance Heat
cytokine 4 97.68 Very High Very High Very High
Inflammation 3 97.48 Very High Very High Very High
palliative 2 5.00 Very Low Very Low Very Low
visual analogue scale 1 5.00 Very Low Very Low Very Low
vincristine 1 5.00 Very Low Very Low Very Low
tolerance 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
INFLAMMATION 3 97.48 Very High Very High Very High
Chronic Disease 5 73.60 Quite High
Anaemia 104 72.64 Quite High
Cancer 66 71.32 Quite High
Lymphatic System Cancer 23 50.00 Quite Low
Hypoxia 2 43.20 Quite Low
Fatigue 6 5.00 Very Low Very Low Very Low
Solid Tumor 5 5.00 Very Low Very Low Very Low
Lymphoproliferative Disease 4 5.00 Very Low Very Low Very Low
Aplasia 4 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Inflammatory cytokines induce the expression of the most important iron distribution regulator hepcidin, which in turn down-regulates and increases degradation of ferroportin, the sole exporter of iron from within the cells to the plasma compartment (Roy and Andrews 2005; Nemeth and Ganz 2006).
Positive_regulation (increases) of Protein_catabolism (degradation) of ferroportin in plasma associated with inflammation and cytokine
1) Confidence 0.02 Published 2008 Journal Therapeutics and Clinical Risk Management Section Body Doc Link PMC2504072 Disease Relevance 0.61 Pain Relevance 0.22

General Comments

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