INT241967

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Context Info
Confidence 0.17
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0
Pain Relevance 0.16

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

Golgi apparatus (Grm7) plasma membrane (Grm7) neurological system process (Grm7)
protein complex (Grm7) signal transducer activity (Grm7)
Grm7 (Rattus norvegicus)
Acpt (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 44 92.24 High High
Glutamate receptor 3 50.00 Quite Low
Dorsal horn 1 32.56 Quite Low
noradrenaline 3 10.56 Low Low
depression 23 7.76 Low Low
agonist 9 5.00 Very Low Very Low Very Low
Action potential 7 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 23 7.76 Low Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It seems likely that these effects are mediated through mGluR4 and/or mGluR8 since, at the concentration we used, ACPT-1 has similar affinity for these two receptors (approximately 8 nM; De Colle et al., 2000) and a comparatively low affinity for mGluR7.
mGluR7 Binding (affinity) of ACPT
1) Confidence 0.17 Published 2007 Journal Neuroscience Section Body Doc Link PMC2504724 Disease Relevance 0 Pain Relevance 0.16

General Comments

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