INT241969

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.35
Pain Relevance 0.27

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Grm8, Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) protein complex (Prkaca) cytoplasm (Prkaca)
Grm8 (Rattus norvegicus)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Glutamate 44 95.64 Very High Very High Very High
depression 23 87.28 High High
Glutamate receptor 3 50.00 Quite Low
agonist 9 5.00 Very Low Very Low Very Low
Action potential 7 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
noradrenaline 3 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 23 87.28 High High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
The ability of mGluR to activate PKA, and for PKA to inhibit mGluRs raises very interesting possibilities with respect to feedback regulation of glutamate release.


mGluR Positive_regulation (activate) of PKA associated with glutamate
1) Confidence 0.05 Published 2007 Journal Neuroscience Section Body Doc Link PMC2504724 Disease Relevance 0.35 Pain Relevance 0.27

General Comments

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