INT241970

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Context Info
Confidence 0.05
First Reported 2007
Last Reported 2007
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.36
Pain Relevance 0.24

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

cytosol (Prkaca) nucleoplasm (Prkaca) mitochondrion (Prkaca)
Golgi apparatus (Prkaca) plasma membrane (Prkaca) nucleus (Prkaca)
Anatomy Link Frequency
synapses 2
Acpt (Rattus norvegicus)
Prkaca (Rattus norvegicus)
Pain Link Frequency Relevance Heat
depression 23 100.00 Very High Very High Very High
Glutamate 44 66.96 Quite High
Glutamate receptor 3 50.00 Quite Low
noradrenaline 3 10.72 Low Low
agonist 9 5.00 Very Low Very Low Very Low
Action potential 7 5.00 Very Low Very Low Very Low
tetrodotoxin 6 5.00 Very Low Very Low Very Low
gABA 4 5.00 Very Low Very Low Very Low
Calcium channel 4 5.00 Very Low Very Low Very Low
Neurotransmitter 3 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Depression 23 100.00 Very High Very High Very High

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
It is unlikely that PKA activation underlies the mGluR depression of eEPSCs at layer V synapses, since eEPSC amplitude was enhanced by forskolin, and the depression induced by ACPT-1 persisted in the presence of an AC inhibitor.
ACPT Positive_regulation (induced) of Positive_regulation (activation) of PKA in synapses associated with depression
1) Confidence 0.05 Published 2007 Journal Neuroscience Section Body Doc Link PMC2504724 Disease Relevance 0.36 Pain Relevance 0.24

General Comments

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