INT242002

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Context Info
Confidence 0.29
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.47
Pain Relevance 0

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

nucleus (Tcf7) DNA binding (Tcf7)
Anatomy Link Frequency
nucleus 1
Tcf7 (Mus musculus)
Pain Link Frequency Relevance Heat
Inflammation 2 5.00 Very Low Very Low Very Low
COX2 1 5.00 Very Low Very Low Very Low
cytokine 1 5.00 Very Low Very Low Very Low
Angina 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Familial Adenomatous Polyposis 4 87.64 High High
Mesothelioma 110 84.48 Quite High
Cancer 33 71.68 Quite High
Malignant Neoplastic Disease 21 50.00 Quite Low
Apoptosis 12 17.28 Low Low
Infection 16 5.00 Very Low Very Low Very Low
Metastasis 4 5.00 Very Low Very Low Very Low
Genetic Predisposition To Disease 4 5.00 Very Low Very Low Very Low
Disease 4 5.00 Very Low Very Low Very Low
Neurofibromatosis 2 3 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
-catenin to escape ubiquination, and enter the nucleus where it can bind to T-cell factor/lymphoid-enhancer factor (Tcf/Lef) transcription factor proteins thereby activating transcription of downstream effectors [45].
Transcription (transcription) of Tcf in nucleus
1) Confidence 0.29 Published 2008 Journal J Carcinog Section Body Doc Link PMC2507706 Disease Relevance 0.47 Pain Relevance 0

General Comments

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