INT242142

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Context Info
Confidence 0.65
First Reported 2008
Last Reported 2010
Negated 0
Speculated 0
Reported most in Body
Documents 4
Total Number 4
Disease Relevance 1.07
Pain Relevance 0.11

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

unfolded protein binding (Dnajc5) protein folding (Dnajc5) plasma membrane (Dnajc5)
Anatomy Link Frequency
T cells 1
Dnajc5 (Mus musculus)
Pain Link Frequency Relevance Heat
Central nervous system 14 79.32 Quite High
Inflammation 12 72.40 Quite High
agonist 18 37.76 Quite Low
cytokine 4 32.96 Quite Low
Eae 2 27.92 Quite Low
Hippocampus 14 27.68 Quite Low
Kinase C 26 5.00 Very Low Very Low Very Low
withdrawal 13 5.00 Very Low Very Low Very Low
depression 12 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Drug Induced Neurotoxicity 24 96.56 Very High Very High Very High
Lifespan 3 86.32 High High
Disease 146 83.52 Quite High
INFLAMMATION 14 72.40 Quite High
Malaria 20 65.76 Quite High
Immunization 18 60.40 Quite High
Creutzfeldt Jakob Disease 12 49.96 Quite Low
Disease Progression 3 44.40 Quite Low
Alzheimer's Dementia 12 33.12 Quite Low
Toxicity 16 31.48 Quite Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Interestingly, the cSP peptide completely blocks A?
Gene_expression (peptide) of cSP
1) Confidence 0.65 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.27 Pain Relevance 0.04
binding site in Fz is homologous to cSP and that this is a relevant target for A?
Gene_expression (homologous) of cSP
2) Confidence 0.65 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.43 Pain Relevance 0.04
The changes in CSP expression are of particular interest, as it has been shown that deletion of the CSP gene in mice (CSP?
Gene_expression (expression) of CSP
3) Confidence 0.23 Published 2010 Journal ASN NEURO Section Body Doc Link PMC2954441 Disease Relevance 0.16 Pain Relevance 0
producing CSP specific CD4+ T cells [29], [30].
Gene_expression (producing) of CSP in T cells
4) Confidence 0.03 Published 2009 Journal PLoS ONE Section Body Doc Link PMC2749339 Disease Relevance 0.20 Pain Relevance 0.04

General Comments

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