INT242148

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Context Info
Confidence 0.35
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 2
Disease Relevance 1.06
Pain Relevance 0.04

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Central nervous system 12 77.28 Quite High
depression 12 42.92 Quite Low
agonist 18 30.24 Quite Low
Hippocampus 6 25.64 Quite Low
Eae 2 20.40 Low Low
nMDA receptor 2 12.68 Low Low
Kinase C 26 5.00 Very Low Very Low Very Low
cINOD 8 5.00 Very Low Very Low Very Low
Inflammation 8 5.00 Very Low Very Low Very Low
Nicotine 6 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 122 95.92 Very High Very High Very High
Drug Induced Neurotoxicity 24 89.04 High High
Neurodegenerative Disease 20 87.60 High High
Manic Depressive Disorder 4 77.52 Quite High
Alzheimer's Dementia 10 68.96 Quite High
Targeted Disruption 14 60.32 Quite High
Amyloid Plaque 12 48.56 Quite Low
Depression 12 42.92 Quite Low
Toxicity 14 29.44 Quite Low
Apoptosis 26 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
insults suggesting that a sustained loss of the Wnt signaling function may be involved in the A?
Negative_regulation (involved) of Negative_regulation (loss) of Wnt
1) Confidence 0.35 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.72 Pain Relevance 0
binding to Fz and prevents inhibition of the Wnt signaling cascade.
Negative_regulation (prevents) of Negative_regulation (inhibition) of Wnt
2) Confidence 0.35 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.34 Pain Relevance 0.04

General Comments

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