INT242150

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Context Info
Confidence 0.42
First Reported 2008
Last Reported 2008
Negated 0
Speculated 0
Reported most in Body
Documents 1
Total Number 1
Disease Relevance 0.65
Pain Relevance 0.31

This is a graph with borders and nodes. Maybe there is an Imagemap used so the nodes may be linking to some Pages.

plasma membrane (Wnt2) molecular_function (Wnt2) cell-cell signaling (Wnt2)
cytoplasm (Wnt2)
Anatomy Link Frequency
neurons 2
Wnt2 (Rattus norvegicus)
Pain Link Frequency Relevance Heat
Inflammation 4 73.16 Quite High
cINOD 4 67.40 Quite High
Hippocampus 3 50.32 Quite High
agonist 9 47.16 Quite Low
Kinase C 13 35.40 Quite Low
Eae 1 6.84 Low Low
Central nervous system 6 5.00 Very Low Very Low Very Low
depression 6 5.00 Very Low Very Low Very Low
Nicotine 3 5.00 Very Low Very Low Very Low
Pyramidal cell 1 5.00 Very Low Very Low Very Low
Disease Link Frequency Relevance Heat
Disease 61 94.00 High High
Targeted Disruption 7 92.40 High High
Drug Induced Neurotoxicity 12 77.56 Quite High
INFLAMMATION 5 73.16 Quite High
Toxicity 7 57.00 Quite High
Apoptosis 13 36.36 Quite Low
Lifespan 1 9.52 Low Low
Neurodegenerative Disease 10 5.00 Very Low Very Low Very Low
Depression 6 5.00 Very Low Very Low Very Low
Amyloid Plaque 6 5.00 Very Low Very Low Very Low

Sentences Mentioned In

Key: Protein Mutation Event Anatomy Negation Speculation Pain term Disease term
Compounds such as IBU-PO, which mimic the activation of the Wnt signaling pathway, could eventually rescue neurons from cytotoxicity through GSK-3?
Positive_regulation (through) of Positive_regulation (activation) of Wnt in neurons
1) Confidence 0.42 Published 2008 Journal Mol Neurodegener Section Body Doc Link PMC2515306 Disease Relevance 0.65 Pain Relevance 0.31

General Comments

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